Gene information
Official symbol MIR133A1
Official full name microRNA 133a-1
Gene type microRNA
Chromosome18q11.2
Alias symbolhsa-mir-133a-1
Previous symbolMIRN133A1
Gene familyMicroRNA MIR133 family
Resources
Entrez Gene 406922
HGNC HGNC:31517
Ensembl ENSG00000283927
UCSC uc021uib.1
GO terms: 139 records
GO Description Category LogP Number of genes Detail
GO:0001933 negative regulation of protein phosphorylation GO Biological Processes -19.8214973 59 More
GO:0003729 mRNA binding GO Molecular Functions -83.3296105 82 More
GO:0003730 mRNA 3'-UTR binding GO Molecular Functions -66.9774057 54 More
GO:0006469 negative regulation of protein kinase activity GO Biological Processes -12.6852914 37 More
GO:0006937 regulation of muscle contraction GO Biological Processes -20.8046481 43 More
GO:0006942 regulation of striated muscle contraction GO Biological Processes -11.0877013 23 More
GO:0007346 regulation of mitotic cell cycle GO Biological Processes -10.6017433 22 More
GO:0008016 regulation of heart contraction GO Biological Processes -27.6827716 55 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0010453 regulation of cell fate commitment GO Biological Processes -3.57905448 8 More
GO:0010455 positive regulation of cell fate commitment GO Biological Processes -4.12684621 3 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0010564 regulation of cell cycle process GO Biological Processes -6.45429517 20 More
GO:0010611 regulation of cardiac muscle hypertrophy GO Biological Processes -13.5611908 22 More
GO:0010614 negative regulation of cardiac muscle hypertrophy GO Biological Processes -8.32112795 7 More
GO:0010656 negative regulation of muscle cell apoptotic process GO Biological Processes -14.6475350 20 More
GO:0010660 regulation of muscle cell apoptotic process GO Biological Processes -26.1774267 35 More
GO:0010662 regulation of striated muscle cell apoptotic process GO Biological Processes -17.3771355 22 More
GO:0010665 regulation of cardiac muscle cell apoptotic process GO Biological Processes -17.8825743 22 More
GO:0010830 regulation of myotube differentiation GO Biological Processes -3.96920305 9 More
GO:0010831 positive regulation of myotube differentiation GO Biological Processes -3.6481831 3 More
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO Biological Processes -2.85984497 3 More
GO:0010948 negative regulation of cell cycle process GO Biological Processes -6.78057192 13 More
GO:0010959 regulation of metal ion transport GO Biological Processes -23.6318171 71 More
GO:0010984 regulation of lipoprotein particle clearance GO Biological Processes -13.0318362 16 More
GO:0010985 negative regulation of lipoprotein particle clearance GO Biological Processes -8.96527714 10 More
GO:0010988 regulation of low-density lipoprotein particle clearance GO Biological Processes -8.17037988 10 More
GO:0010989 negative regulation of low-density lipoprotein particle clearance GO Biological Processes -8.80074885 9 More
GO:0014741 negative regulation of muscle hypertrophy GO Biological Processes -8.77845673 13 More
GO:0014743 regulation of muscle hypertrophy GO Biological Processes -14.1608908 23 More
GO:0016441 post-transcriptional gene silencing GO Biological Processes -100 124 More
GO:0019722 calcium-mediated signaling GO Biological Processes -11.6647584 29 More
GO:0019932 second-messenger-mediated signaling GO Biological Processes -19.1717114 46 More
GO:0022898 regulation of transmembrane transporter activity GO Biological Processes -11.1988499 41 More
GO:0030336 negative regulation of cell migration GO Biological Processes -30.9008082 37 More
GO:0030371 translation repressor activity GO Molecular Functions -100 82 More
GO:0031047 gene silencing by RNA GO Biological Processes -100 125 More
GO:0031400 negative regulation of protein modification process GO Biological Processes -17.0986645 70 More
GO:0032409 regulation of transporter activity GO Biological Processes -16.9480646 53 More
GO:0032410 negative regulation of transporter activity GO Biological Processes -23.0637580 21 More
GO:0032412 regulation of ion transmembrane transporter activity GO Biological Processes -9.90560995 38 More
GO:0032413 negative regulation of ion transmembrane transporter activity GO Biological Processes -14.5724579 14 More
GO:0033673 negative regulation of kinase activity GO Biological Processes -12.5521161 39 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034763 negative regulation of transmembrane transport GO Biological Processes -22.14661 42 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0034766 negative regulation of ion transmembrane transport GO Biological Processes -15.824921 16 More
GO:0035194 post-transcriptional gene silencing by RNA GO Biological Processes -100 124 More
GO:0035195 miRNA-mediated gene silencing GO Biological Processes -100 124 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0042058 regulation of epidermal growth factor receptor signaling pathway GO Biological Processes -3.75205908 5 More
GO:0042326 negative regulation of phosphorylation GO Biological Processes -20.6187298 64 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0043266 regulation of potassium ion transport GO Biological Processes -7.37974754 20 More
GO:0043267 negative regulation of potassium ion transport GO Biological Processes -7.26795046 12 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043271 negative regulation of ion transport GO Biological Processes -19.3914052 40 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043409 negative regulation of MAPK cascade GO Biological Processes -13.5471736 35 More
GO:0043502 regulation of muscle adaptation GO Biological Processes -16.8828965 29 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0045182 translation regulator activity GO Molecular Functions -97.0300828 82 More
GO:0045786 negative regulation of cell cycle GO Biological Processes -11.4279863 20 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045930 negative regulation of mitotic cell cycle GO Biological Processes -12.1211141 17 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048662 negative regulation of smooth muscle cell proliferation GO Biological Processes -21.7509412 30 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051147 regulation of muscle cell differentiation GO Biological Processes -17.2781401 19 More
GO:0051149 positive regulation of muscle cell differentiation GO Biological Processes -18.0749983 16 More
GO:0051153 regulation of striated muscle cell differentiation GO Biological Processes -11.0877013 23 More
GO:0051155 positive regulation of striated muscle cell differentiation GO Biological Processes -9.79559611 9 More
GO:0051271 negative regulation of cellular component movement GO Biological Processes -29.9238399 37 More
GO:0051279 regulation of release of sequestered calcium ion into cytosol GO Biological Processes -5.25087734 14 More
GO:0051282 regulation of sequestering of calcium ion GO Biological Processes -7.93009971 22 More
GO:0051348 negative regulation of transferase activity GO Biological Processes -13.2006110 43 More
GO:0051924 regulation of calcium ion transport GO Biological Processes -18.2498286 49 More
GO:0051926 negative regulation of calcium ion transport GO Biological Processes -11.4193150 11 More
GO:0055117 regulation of cardiac muscle contraction GO Biological Processes -9.51337974 19 More
GO:0060306 regulation of membrane repolarization GO Biological Processes -5.46127869 10 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070373 negative regulation of ERK1 and ERK2 cascade GO Biological Processes -5.87762530 7 More
GO:0071900 regulation of protein serine/threonine kinase activity GO Biological Processes -19.5794055 63 More
GO:0071901 negative regulation of protein serine/threonine kinase activity GO Biological Processes -13.7044922 29 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090257 regulation of muscle system process GO Biological Processes -33.9441291 67 More
GO:0098900 regulation of action potential GO Biological Processes -5.92071483 13 More
GO:0098903 regulation of membrane repolarization during action potential GO Biological Processes -4.38551308 3 More
GO:0099623 regulation of cardiac muscle cell membrane repolarization GO Biological Processes -3.70345918 7 More
GO:1900407 regulation of cellular response to oxidative stress GO Biological Processes -21.4526227 33 More
GO:1901016 regulation of potassium ion transmembrane transporter activity GO Biological Processes -4.99917325 6 More
GO:1901017 negative regulation of potassium ion transmembrane transporter activity GO Biological Processes -7.29825318 6 More
GO:1901019 regulation of calcium ion transmembrane transporter activity GO Biological Processes -4.15488175 6 More
GO:1901020 negative regulation of calcium ion transmembrane transporter activity GO Biological Processes -6.16487283 6 More
GO:1901031 regulation of response to reactive oxygen species GO Biological Processes -8.30091899 13 More
GO:1901032 negative regulation of response to reactive oxygen species GO Biological Processes -7.95539378 6 More
GO:1901184 regulation of ERBB signaling pathway GO Biological Processes -3.96203474 12 More
GO:1901379 regulation of potassium ion transmembrane transport GO Biological Processes -5.20214986 7 More
GO:1901380 negative regulation of potassium ion transmembrane transport GO Biological Processes -6.94090814 6 More
GO:1901987 regulation of cell cycle phase transition GO Biological Processes -7.48321149 17 More
GO:1901988 negative regulation of cell cycle phase transition GO Biological Processes -6.79968458 12 More
GO:1901990 regulation of mitotic cell cycle phase transition GO Biological Processes -9.06841215 17 More
GO:1901991 negative regulation of mitotic cell cycle phase transition GO Biological Processes -8.19381421 12 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1902806 regulation of cell cycle G1/S phase transition GO Biological Processes -9.32363308 14 More
GO:1902807 negative regulation of cell cycle G1/S phase transition GO Biological Processes -8.70120563 10 More
GO:1902882 regulation of response to oxidative stress GO Biological Processes -20.0046302 33 More
GO:1902883 negative regulation of response to oxidative stress GO Biological Processes -9.05707121 7 More
GO:1903169 regulation of calcium ion transmembrane transport GO Biological Processes -8.80532519 28 More
GO:1903170 negative regulation of calcium ion transmembrane transport GO Biological Processes -8.34191356 8 More
GO:1903201 regulation of oxidative stress-induced cell death GO Biological Processes -18.4601079 28 More
GO:1903202 negative regulation of oxidative stress-induced cell death GO Biological Processes -17.0330784 23 More
GO:1903205 regulation of hydrogen peroxide-induced cell death GO Biological Processes -7.29825318 6 More
GO:1903206 negative regulation of hydrogen peroxide-induced cell death GO Biological Processes -7.13135320 9 More
GO:1903231 mRNA base-pairing post-transcriptional repressor activity GO Molecular Functions -100 82 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
GO:1903817 negative regulation of voltage-gated potassium channel activity GO Biological Processes -8.21981407 6 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904063 negative regulation of cation transmembrane transport GO Biological Processes -14.8002568 15 More
GO:1904705 regulation of vascular associated smooth muscle cell proliferation GO Biological Processes -22.4951686 19 More
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation GO Biological Processes -11.2917234 16 More
GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential GO Biological Processes -4.91375876 3 More
GO:1905032 negative regulation of membrane repolarization during cardiac muscle cell action potential GO Biological Processes -5.84889250 3 More
GO:1905207 regulation of cardiocyte differentiation GO Biological Processes -9.12694220 13 More
GO:1905209 positive regulation of cardiocyte differentiation GO Biological Processes -9.78130162 11 More
GO:1905699 regulation of xenobiotic detoxification by transmembrane export across the plasma membrane GO Biological Processes -7.66850466 5 More
GO:1905700 negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane GO Biological Processes -7.66850466 5 More
GO:2000045 regulation of G1/S transition of mitotic cell cycle GO Biological Processes -10.1341432 14 More
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle GO Biological Processes -9.22212459 10 More
GO:2000146 negative regulation of cell motility GO Biological Processes -30.256132 37 More
GO:2000291 regulation of myoblast proliferation GO Biological Processes -11.9631058 8 More
GO:2000818 negative regulation of myoblast proliferation GO Biological Processes -10.9990575 6 More
GO:2001023 regulation of response to drug GO Biological Processes -7.47914083 5 More
GO:2001024 negative regulation of response to drug GO Biological Processes -7.66850466 5 More
GO:2001257 regulation of cation channel activity GO Biological Processes -11.2578208 33 More
GO:2001258 negative regulation of cation channel activity GO Biological Processes -15.1930683 13 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa05206 MicroRNAs in cancer KEGG Pathway -100 81 More
Related studies: 40 records
Molecular factor Omics type Application Objective MI type Reference
hsa-miR-133a-3p transcriptomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Wang GK et al. Eur Heart J. 2010
hsa-miR-133a-5p transcriptomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Wang GK et al. Eur Heart J. 2010
hsa-miR-133a-3p transcriptomics good predictor acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Gidlof O et al. Cardiology. 2011
hsa-miR-133a-5p transcriptomics good predictor acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Gidlof O et al. Cardiology. 2011
hsa-miR-133a-3p transcriptomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Wang R et al. Intern Med. 2011
hsa-miR-133a-5p transcriptomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Wang R et al. Intern Med. 2011
hsa-miR-133a-3p transcriptomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Eitel I et al. Am Heart J. 2012
hsa-miR-133a-5p transcriptomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Eitel I et al. Am Heart J. 2012
hsa-miR-133a-3p transcriptomics excellent predictor acute myocardial infarction[diagnosis] acute myocardial infarction Li YQ et al. Clinics (Sao Paulo). 2013
hsa-miR-133a-5p transcriptomics excellent predictor acute myocardial infarction[diagnosis] acute myocardial infarction Li YQ et al. Clinics (Sao Paulo). 2013
hsa-miR-133a-3p transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Wang F et al. J Transl Med. 2013
hsa-miR-133a-5p transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Wang F et al. J Transl Med. 2013
hsa-miR-133a-3p transcriptomics excellent predictor acute myocardial infarction[diagnosis] acute myocardial infarction Peng L et al. Diagn Pathol. 2014
hsa-miR-133a-5p transcriptomics excellent predictor acute myocardial infarction[diagnosis] acute myocardial infarction Peng L et al. Diagn Pathol. 2014
hsa-miR-133a-3p transcriptomics good predictor type 5 myocardial infarction[diagnosis] type 5 myocardial infarction Yao Y et al. PLoS One. 2014
hsa-miR-133a-3p transcriptomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Ji Q et al. Minerva Cardioangiol. 2015
hsa-miR-133a-5p transcriptomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Ji Q et al. Minerva Cardioangiol. 2015
hsa-miR-133a-3p transcriptomics poor predictor acute myocardial infarction[diagnosis] acute myocardial infarction Ke-Gang J et al. Medicine (Baltimore). 2016
hsa-miR-133a-5p transcriptomics poor predictor acute myocardial infarction[diagnosis] acute myocardial infarction Ke-Gang J et al. Medicine (Baltimore). 2016
hsa-miR-133a-3p transcriptomics adverse events[prognosis (bad)] acute myocardial infarction Ke-Gang J et al. Medicine (Baltimore). 2016
hsa-miR-133a-5p transcriptomics adverse events[prognosis (bad)] acute myocardial infarction Ke-Gang J et al. Medicine (Baltimore). 2016
hsa-miR-133a-3p transcriptomics adverse events[prognosis (bad)] acute myocardial infarction Ke-Gang J et al. Medicine (Baltimore). 2016
hsa-miR-133a-5p transcriptomics adverse events[prognosis (bad)] acute myocardial infarction Ke-Gang J et al. Medicine (Baltimore). 2016
hsa-miR-133a-3p transcriptomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Cortez-Dias N et al. Circ J. 2016
hsa-miR-133a-3p transcriptomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Yuan L et al. Clin Lab. 2016
hsa-miR-133a-5p transcriptomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Yuan L et al. Clin Lab. 2016
hsa-miR-133a-3p transcriptomics ventricular fibrillation[prognosis (bad)] ST elevation myocardial infarction Bostjancic E et al. Biomed Pharmacother. 2018
hsa-miR-133a-5p transcriptomics ventricular fibrillation[prognosis (bad)] ST elevation myocardial infarction Bostjancic E et al. Biomed Pharmacother. 2018
hsa-miR-133a-3p transcriptomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Goldbergova MP et al. Bratisl Lek Listy. 2018
hsa-miR-133a-5p transcriptomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Goldbergova MP et al. Bratisl Lek Listy. 2018
hsa-miR-133a-3p transcriptomics excellent predictor acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Liu G et al. J Thorac Dis. 2018
hsa-miR-133a-5p transcriptomics excellent predictor acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Liu G et al. J Thorac Dis. 2018
hsa-miR-133a-3p transcriptomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Pinchi E et al. J Cell Mol Med. 2019
hsa-miR-133a-5p transcriptomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Pinchi E et al. J Cell Mol Med. 2019
hsa-miR-133a-3p transcriptomics death[prognosis (bad)] acute myocardial infarction Hromadka M et al. Dis Markers. 2019
hsa-miR-133a-5p transcriptomics death[prognosis (bad)] acute myocardial infarction Hromadka M et al. Dis Markers. 2019
hsa-miR-133a-3p transcriptomics acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Mompeon A et al. Sci Rep. 2020
hsa-miR-133a-5p transcriptomics acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Mompeon A et al. Sci Rep. 2020
hsa-miR-133a-3p transcriptomics acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Mompeon A et al. Sci Rep. 2020
hsa-miR-133a-5p transcriptomics acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Mompeon A et al. Sci Rep. 2020
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